- Opportunistic computed tomography-based vertebral attenuation for osteoporosis screening. [Journal Article]Rev Assoc Med Bras (1992). 2026; 72(10):e20260914.RA
- CONCLUSIONS: Opportunistic sagittal lumbar Hounsfield Unit measurements, particularly at L1, provide high diagnostic accuracy and reproducibility for identifying osteoporosis on routine abdominal computed tomography without requiring additional imaging or radiation exposure. This protocol may facilitate early opportunistic screening for osteoporosis and support timely referral for dual-energy X-ray absorptiometry assessment.
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- Propofol versus remifentanil sedation for elective gastroscopy: a randomized controlled trial. [Randomized Controlled Trial]
- CONCLUSIONS: Despite comparable patient-reported recovery quality, propofol was associated with substantially fewer perioperative adverse events (0 vs. 61.4%) and higher endoscopist satisfaction, supporting its preferential use in routine elective gastroscopy sedation.
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- A modified Rapid Emergency Medicine Score incorporating C-reactive protein for mortality prediction in septic shock. [Journal Article]Rev Assoc Med Bras (1992). 2026; 72(10):e20260890.RA
- CONCLUSIONS: Rapid Emergency Medicine Score incorporating C-reactive protein showed moderate discrimination for 30-day mortality in this exploratory development cohort but did not demonstrate superior discrimination compared with National Early Warning Score, Modified Early Warning Score, or quick Sequential Organ Failure Assessment. Because Rapid Emergency Medicine Score incorporating C-reactive protein was developed and evaluated in the same cohort, these findings should be considered hypothesis-generating. Independent external validation is required before its clinical utility can be established.
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- Potentially avoidable computed tomography after positive ultrasonography in appendicitis. [Journal Article]
- CONCLUSIONS: Computed tomography remained frequent even after ultrasonography established the diagnosis, with no effect on emergency department length of stay, generating avoidable radiation and costs concentrated in children. Reducing computed tomography after a positive ultrasonography is a feasible opportunity to improve resource utilization while preserving patient safety.
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- Partner hygiene-related behaviors and vaginitis subtypes: an exploratory observational study. [Journal Article]Rev Assoc Med Bras (1992). 2026; 72(10):e20260806.RA
- CONCLUSIONS: Lower partner hygiene scores were associated with dysbiosis-predominant vaginitis phenotypes, particularly bacterial vaginosis and trichomoniasis. Although no association was observed with short-term recurrence, these findings are hypothesis-generating and require confirmation in larger prospective studies.
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- The effect of micronutrient supplementation on women's sexual desire: a systematic review and meta-analysis study. [Systematic Review]
- CONCLUSIONS: This systematic review suggests a potential role for micronutrients, but the evidence is weak and highly inconsistent. High-quality, low-heterogeneity research is urgently needed.
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- Evaluation of the ranawat triangle method for determining hip rotation center in total hip arthroplasty among Turkish patients. [Journal Article]
- CONCLUSIONS: The Ranawat triangle method method demonstrated excellent accuracy in predicting the vertical (Y-axis) position of the anatomical femoral head center but showed moderate lateral (X-axis) deviations in over 40% of cases. Despite its limitations in lateral offset prediction, it may serve as a practical reference method for preoperative planning, particularly for estimating the vertical position of the hip rotation center in Turkish total hip arthroplasty patients.
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- Moral distress arising from professionalism dilemmas among medical interns. [Journal Article]
- CONCLUSIONS: Moral distress is a prevalent phenomenon in medical education. The adapted checklist demonstrated semantic and conceptual equivalence to the original and may serve as a valuable tool to identify, quantify, and understand moral distress among medical students in clinical training.
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- Female sexual dysfunction in anti-synthetase syndrome. [Journal Article]
- CONCLUSIONS: Sexual dysfunction is highly prevalent in women with anti-synthetase syndrome and appears intrinsically associated with the disease. Cognitive behavioral therapy represents a promising non-pharmacological strategy to improve sexual function, distress, and fatigue in this population.
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- Do hospitalized children with obesity lose more weight than eutrophic ones? [Journal Article]Rev Assoc Med Bras (1992). 2026; 72(10):e20251923.RA
- CONCLUSIONS: Overweight at hospital admission was associated with a longer hospital stay and progressive weight loss during hospitalization.
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- Fundus camera and artificial intelligence for diabetic retinopathy screening in a São Paulo shelter. [Journal Article]
- CONCLUSIONS: The Eyer® device demonstrated operational feasibility for ocular screening by trained non-ophthalmologists. The high prevalence of media opacities and non-diabetic retinopathy conditions compromised artificial intelligence performance, highlighting the need for broader screening strategies in elderly and socially vulnerable populations.
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- Association of Vascular Endothelial Growth Factor A-2549 I/D polymorphism with polycystic ovary syndrome susceptibility in Turkish women. [Journal Article]
- CONCLUSIONS: In this Turkish case-control sample, the Vascular Endothelial Growth Factor A-2549 insertion/deletion detection/deletion genotype was more frequent among women with polycystic ovary syndrome than among controls. This observed association does not establish causality, a functional effect, phenotype-specific relevance, or clinical utility. Deviation from Hardy-Weinberg equilibrium in controls, residual confounding from incomplete matching, limited power, and lack of functional validation make the finding preliminary. Independent validation in larger, well-matched cohorts with prespecified genotyping quality control, phenotype stratification, and functional studies is required.
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- Rational Drug Use Support System: design, artificial intelligence integration, and pilot feasibility trial. [Journal Article]
- CONCLUSIONS: The findings suggest that the "Rational Drug Use Support System" appears feasible for implementation in telemedicine and clinical settings to support rational drug use and patient engagement in chronic disease management. However, larger controlled studies are warranted to confirm these preliminary findings.
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- The patient statute (Law No. 15,378/2026) and the redefinition of medical authority: autonomy, dignity, and legal certainty at the bedside. [Editorial]Rev Assoc Med Bras (1992). 2026; 72(9):e20260777.RA
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- Lipedema research (2000-2025): a global bibliometric analysis with evidence of an emerging immunological paradigm. [Journal Article]
- CONCLUSIONS: Lipedema research is undergoing rapid exponential expansion driven by growing global recognition of a historically neglected condition. The accelerating immunological trend, with consistently higher citation impact, indicates an accelerating paradigm shift toward chronic adipose tissue inflammation as a unifying pathophysiological framework.
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