Higgins SP, Freemark M, Prose NS Acanthosis nigricans: A practical approach to evaluation and management. [Journal Article] Dermatol Online J 2008; 14(9):2.
Acanthosis nigricans is a dermatosis characterized by thickened, hyperpigmented plaques, typically of the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize acanthosis nigricans; it heralds disorders ranging from endocrinologic disturbances to malignancy. In this review, we discuss the pathogenesis of acanthosis nigricans and its clinical implications and management.
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