- Patient characteristics and the safety of stent placement for malignant vena cava syndrome in Japan: a nationwide analysis. [Multicenter Study]
- CONCLUSIONS: Stent placement for malignant vena cava obstruction demonstrated an overall complication rate of 10.6% with no serious adverse events requiring invasive intervention.
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- Thresholds for clinical importance to improve interpretation of the EORTC QLQ-COMU26 communication questionnaire. [Journal Article]
- CONCLUSIONS: This study established TCIs with high diagnostic accuracy for the EORTC QLQ-COMU26, supporting its use in clinical practice and research. The findings suggest that the questionnaire can identify patients who report low communication for specific domains and help improve communication in clinical settings.
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- Biopsychosocial dimensions of cancer and spiritual coping strategies: a phenomenological study of patient experiences. [Review]
- CONCLUSIONS: The findings showed that living with cancer is a multidimensional process shaped by changing perceptions and reactions and interconnected physical, psychological, and social difficulties. Spirituality emerged as a personal coping resource used by some participants to give meaning to the illness experience, maintain hope, and find strength to endure. However, differences in participants' perceptions of coping indicated that the use of spiritual resources was not always accompanied by a strong perception of coping. These findings highlight the importance of addressing the changing biopsychosocial needs and personal coping resources of individuals living with cancer through an individualized and holistic approach.
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- Application of machine learning to identify risk factors for bloodstream infections caused by different antimicrobial resistance phenotypes in chemotherapy patients. [Journal Article]
- CONCLUSIONS: Multi-label machine learning approaches may help disentangle the complex etiologies of BSIs in cancer patients by identifying associations between host factors, prior MDRO infection, and chemotherapy class within confirmed BSI episodes, informing future hypothesis generation.
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- Delayed and selective bone health assessment following cancer diagnosis: a real-world gap in survivorship care. [Journal Article]
- CONCLUSIONS: In our real-world experience within a large private healthcare network, DXA assessment after cancer diagnosis is infrequently performed and often delayed, with marked disparities by sex and cancer type. A substantial burden of low bone mass is already present at the time of evaluation, highlighting missed opportunities for early skeletal risk identification.
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- Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial. [Randomized Controlled Trial]
- CONCLUSIONS: Extraoral PBM demonstrated comparable effectiveness to intraoral for OM prevention in pediatric patients undergoing HDMTX chemotherapy, while reducing application time.
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- Comparative efficacy of interventions for preventing chemotherapy-induced alopecia: a systematic review and network meta-analysis. [Systematic Review]
- CONCLUSIONS: Current low certainty evidence suggests that scalp hypothermia could prevent CIA. Prolonged-scalp hypothermia provides a higher degree of protection, whereas a short duration demonstrates a weaker protective effect. However, this difference was not statistically significant.
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- Association between prophylactic desloratadine use and docetaxel-induced skin toxicities in patients with early-stage breast cancer: an inverse probability-weighted retrospective cohort study. [Journal Article]
- CONCLUSIONS: Desloratadine prophylaxis was associated with lower skin-toxicity risk, particularly for pruritus. Rash risk was lower but imprecisely estimated; HFS risk was not lower. These hypothesis-generating findings warrant validation in a prospective randomized trial.
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- Assessing financial toxicity with COST-FACIT: experience from a tertiary care cancer center. [Journal Article]
- CONCLUSIONS: Our study provides insights into risk factors for FT in a large cancer population. We did not demonstrate a significant association of FT on survival. Further analysis in specific disease groups is needed to better understand these relationships.
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- Digital supportive care in prostate cancer: a systematic review. [Systematic Review]
- CONCLUSIONS: Digital models in prostate cancer care were acceptable and valued for their convenience, flexibility, immediacy of access, tailored content, clinician support, and interactive features, and facilitated self-management through decision-making, symptom management, and informational and psychosocial support. Interpreted through the HOT-fit framework, their value depended on the fit between the technology, its users, and the care setting rather than on technological sophistication alone. Limited attention has been given to digital sexual wellbeing support, and further research is needed on engagement among people with low digital literacy, non-English speakers, and lower-income populations, and on the long-term sustainability of digital models.
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- Altered resting-state functional connectivity in lung cancer patients with comorbid depressive symptoms. [Journal Article]
- CONCLUSIONS: Our findings suggest preliminary associations between depressive symptoms and altered RS-FC in lung cancer patients, with connectivity changes correlating with symptom severity. However, because data on psychotropic medication use, cancer-related symptoms (e.g., pain, fatigue), and treatment details were not systematically collected, these findings should be considered preliminary and hypothesis-generating rather than definitive markers of comorbid depression. Future longitudinal studies with systematic assessment of medication, treatment, and multidimensional symptom burden are needed to determine whether these connectivity patterns specifically reflect depressive symptoms or broader cancer-related sequelae.
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- Implementation of a universal psychosocial screening program across the pediatric cancer treatment trajectory: a standard of care. [Journal Article]
- CONCLUSIONS: We achieved development, implementation, and optimization of a psychosocial screening program across our cancer center.
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- Sleep Quality in Adults with Cancer: Associations with Symptom Burden and Psychological Resilience. [Journal Article]
- CONCLUSIONS: Poor sleep was common among adults with cancer. Mental health and resilience were independently associated with sleep quality beyond clinical characteristics. These findings highlight the relevance of considering psychosocial factors alongside clinical characteristics when assessing sleep problems in supportive oncology care.
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