- Comparative accuracy of large language models and orthopaedic clinicians in knee osteoarthritis and tibial plateau fracture classification systems. [Journal Article]Knee. 2026 Oct 24; 64:104660. [Online ahead of print]KNEE
- CONCLUSIONS: LLM classification accuracy varied across systems and was lower overall than that of orthopaedic surgeons and residents. These findings are limited to the selected educational dataset and evaluation conditions. They do not establish educational or clinical utility; validation in larger, representative datasets is required.
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- Estimated coronal plane alignment of the knee phenotype transitions after imageless ROSA-assisted total knee arthroplasty are frequent but not significantly associated with short-term patient-reported outcomes. [Journal Article]Knee. 2026 Oct 23; 64:104654. [Online ahead of print]KNEE
- CONCLUSIONS: Estimated CPAK phenotype transitions were frequent after imageless ROSA-assisted TKA, but their presence, magnitude and direction were not significantly associated with worse short-term PROMs. Preservation of the estimated preoperative CPAK phenotype may not be necessary for satisfactory short-term outcomes, although confirmation using direct full-length alignment measurements is required.
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- Radiographic patellofemoral differences between end-stage knee rheumatoid arthritis and matched knee osteoarthritis vary by arithmetic hip-knee-ankle-angle-defined coronal alignment. [Journal Article]Knee. 2026 Oct 23; 64:104655. [Online ahead of print]KNEE
- CONCLUSIONS: End-stage KRA showed a distinct radiographic patellofemoral phenotype compared with matched KOA, with several between-disease differences varying by coronal alignment.
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- Evaluations of the hindfoot before and after total knee arthroplasty for patients with varus and valgus knee osteoarthritis. [Journal Article]Knee. 2026 Oct 21; 64:104659. [Online ahead of print]KNEE
- CONCLUSIONS: At 6 months after mechanically aligned TKA, radiographic ankle and hindfoot alignment responses differed between varus and valgus KOA. Because ankle- and hindfoot-specific clinical outcomes and the subtalar joint were not assessed systematically, the clinical significance and mechanisms remain uncertain.
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- Reliability and validity of the My Jump Lab app for assessing vertical jump performance after anterior cruciate ligament reconstruction. [Journal Article]Knee. 2026 Oct 22; 64:104658. [Online ahead of print]KNEE
- CONCLUSIONS: My Jump Lab provides reliable and valid measures of vertical jump performance post-ACLR and may complement RTS assessment when force platforms are unavailable.
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- Prediction model-based comparison of medial stabilized and cruciate-retaining total knee arthroplasty: A two-phase study. [Journal Article]Knee. 2026 Oct 22; 64:104657. [Online ahead of print]KNEE
- CONCLUSIONS: The CR-based prediction model demonstrated moderate internal predictive performance within the study cohort. Within the limitations of this exploratory analysis, no statistically significant difference in postoperative knee flexion was detected between observed MS-TKA outcomes and the flexion predicted under hypothetical CR conditions. Larger externally validated studies with adequate statistical power are required before definitive conclusions regarding implant-specific differences can be drawn.
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- Tibiofemoral kinematics around heel strike associated with heel strike transient in patients after total knee arthroplasty. [Journal Article]Knee. 2026 Oct 22; 64:104656. [Online ahead of print]KNEE
- CONCLUSIONS: Compared with the non-HST group, the HST group showed a greater extension-directed change in flexion angle and a more anterior position of the lateral contact point across the before- and after-HS. These findings suggest that HST is associated with a distinct tibiofemoral kinematic pattern during the terminal swing-to-early stance transition.
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- Reduced knee adduction moments in bicruciate-retaining total knee arthroplasty compared with bicruciate-substituting designs: A contralateral within-patient study. [Journal Article]Knee. 2026 Oct 17; 63:104652. [Online ahead of print]KNEE
- CONCLUSIONS: BCR-TKA was associated with lower first and second peak KAMs despite similar postoperative alignment, whereas KAM impulse and patient-reported outcomes were comparable between the implant designs.
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- Proximal fibular osteotomy for medial compartment knee osteoarthritis: clinical effectiveness and biomechanical rationale: a systematic review. [Review]Knee. 2026 Oct 15; 63:104653. [Online ahead of print]KNEE
- CONCLUSIONS: Current evidence suggests PFO is associated with symptomatic improvement with rapid postoperative recovery, while biomechanical findings support a load-modifying rather than deformity-correcting mechanism. However, confidence in clinical effectiveness and safety is limited by predominantly observational evidence, heterogeneous designs and limited long-term comparative data.
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- Development and validation of a deep learning-based automated Notch Width Index measurement system from anteroposterior knee radiographs. [Journal Article]Knee. 2026 Oct 05; 63:104650. [Online ahead of print]KNEE
- CONCLUSIONS: The method achieved moderate-to-good agreement with expert measurement while ensuring deterministic, examiner-independent reproducibility. Because it was never trained on surgeons' readings, this reflects reproduction of the geometric definition rather than overfitting. The principal barrier is segmentation under domain shift, not the algorithm; the method is best regarded as a reproducible standardization tool for routine anteroposterior views.
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- Quality and clinical implications of AI chatbot responses to common patient questions about total knee arthroplasty: a multidimensional comparative study. [Journal Article]Knee. 2026 Oct 03; 63:104648. [Online ahead of print]KNEE
- CONCLUSIONS: AI chatbot performance for TKA FAQs is domain-dependent across quality, usability, and transparency. These findings have direct implications for orthopedic practice, particularly in preoperative patient counseling and shared decision-making in TKA.
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- Mechanisms underlying the inhibition of chondrocyte apoptosis and inflammatory cytokine expression in knee osteoarthritis by rehmannia glutinosa polysaccharides via PI3K/AKT pathway activation at different concentrations. [Journal Article]Knee. 2026 Oct 02; 63:104647. [Online ahead of print]KNEE
- CONCLUSIONS: Rehmannia glutinosa polysaccharide (RGP) exerts a protective effect on cartilage by activating the PI3K/AKT/mTOR signaling pathway to regulate the mitochondrial apoptosis pathway, thereby inhibiting IL-1β-induced apoptosis and inflammatory responses in knee osteoarthritis chondrocytes.
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- Articular congruence, not neutrality: a systematic review of how native knee geometry shapes load-dependent alignment. [Review]Knee. 2026 Oct 01; 63:104649. [Online ahead of print]KNEE
- CONCLUSIONS: The phenomenon is best interpreted as a geometric load-response of the native knee: unequal M/L contact heights produce coronal inclination, and A/P contact-centroid position produces sagittal behavior. The current literature provides multiple convergent manifestations of this mechanism across WB imaging, axial compression, cadaveric stress testing, JLO manipulation, sagittal geometry, meniscal mechanics, and dynamic in-vivo studies. Clinically, this framework is most directly applicable to native knees with preserved meniscal containment and intact or mildly degenerative compartmental congruence, where static alignment phenotypes should be interpreted together with the load paths that produce them. Future work should directly co-measure ΔJLO, Δh, A/P contact position, and early-flexion tilt in the same standardized protocol.
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- Outcomes of supramalleolar tibial derotational osteotomy in paediatric patients with recurrent patellar dislocation or anterior knee pain and associated torsional malalignment. [Journal Article]Knee. 2026 Sep 30; 63:104644. [Online ahead of print]KNEE
- CONCLUSIONS: Distal tibial derotation osteotomy for patellofemoral instability or pain in children appears to be safe and may be considered as part of the treatment strategy for patients with torsional malalignment, with the potential to reduce recurrence rates associated with isolated MPFL reconstruction.
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