Group A Streptococcus (GAS) pharyngitis remains the leading bacterial cause of acute sore throat worldwide. Surges in GAS infections are driven by hypervirulent strains such as M1UK. The 2025 clinical practice guideline update from the Infectious Diseases Society of America introduces evidence-based recommendations for risk assessment using clinical scoring systems to optimize diagnostic testing and reduce unnecessary antibiotic use. This review examines current diagnostic approaches, treatment protocols, antimicrobial resistance patterns, and emerging therapeutic strategies to support nurse practitioners in delivering evidence-based, stewardship-aligned patient care.

Asthma is a chronic disease that persists into adulthood. Despite available treatments, many adults have poor symptom control. This article reviews the diagnosis of asthma and outlines current Global Initiative for Asthma recommendations for preferred and alternative pharmacologic management of mild-to-moderate asthma in adults.

Today's clinical environments are rife with tools designed to comprehensively account for medical complexity and comorbidities while predicting risk for a host of adverse health-related outcomes. Therefore, it is imperative that advanced practice registered nurses (APRNs) understand the structure and function of these tools, their similarities and differences, their limitations, and strategies for appropriate incorporation into practice. This article offers a practical overview for APRNs, emphasizing clinical implications and guidance for aligning assessment tools with the clinical population of interest to improve care delivery, quality, and patient outcomes.

Renamed from nonalcoholic fatty liver disease in 2023, metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent globally and has potential for serious sequelae. Some patients with MASLD can be managed and followed in primary care, whereas those with clinically significant fibrosis from metabolic dysfunction-associated steatohepatitis (MASH) should be managed in specialty care. This article reviews the pathophysiology, differential diagnosis, and management of MASLD.