In this prospective observational study, we aimed to evaluate the incidence of Helicobacter pylori infection in gallstone disease and to assess its association with different types of gallstones and histopathological findings. It was conducted on 200 patients undergoing cholecystectomy. H. pylori detection was performed using the rapid urease test and histopathological examination. Cholesterol stones constituted 70% of cases, while pigment stones accounted for 30%. The overall incidence of H. pylori infection was 38.5%. A significantly higher prevalence of H. pylori was observed in cholesterol stones (45%) compared to pigment (23.3%). Chronic cholecystitis was present in 88.5%, and incidental carcinoma in situ was found in 2%, all associated with H. pylori positivity. Significant associations were observed between H. pylori status and stone type (p < .05). Our study establishes a significant association between H. pylori infection and gallstone disease, particularly cholesterol stones, and a potential link with premalignant gallbladder conditions.

A retrospective observational study was conducted to determine the success rate of non-operative management of intussusception at the two major paediatric surgical referral hospitals in Kingston, Jamaica, and to compare it to previously reported regional and international benchmarks. Factors affecting the success rate and length of hospital stay were studied. Of 64 cases of radiologically confirmed intussusception among children, non-operative reduction was attempted in 40 (63%), with success in 24 (60%). Patients successfully managed non-operatively had a significantly shorter average (2.08 vs 10.88 days) and median (2 vs 5 days) lengths of stay compared with those managed surgically (p < 0.001).

Academic equity has become a dominant theme in global health and research discourse, yet meaningful structural change often lags behind increasingly sophisticated rhetoric. Through satire, this commentary examines the gap between declarations of commitment and everyday academic practice, illustrating how institutions can enthusiastically champion equity while preserving existing hierarchies of power, authorship, funding, and decision-making. By exaggerating familiar behaviours into "Ten Commandments of Academic Equity Theatre," the article invites readers to reflect on performative inclusiveness and asks whether academia is prepared to move beyond measuring, discussing, and celebrating equity to genuinely sharing it.

The 2025 neonatal resuscitation guidelines, developed jointly by the American Heart Association and the American Academy of Pediatrics, provide evidence-based recommendations for the most crucial actions during delivery and throughout the neonatal period. Ventilation remains the cornerstone of resuscitation, starting with ventilation rates of 30-60/ min, ≥ 30% oxygen for very preterm infants (<32 weeks), guided by pulse oximetry and electrocardiography monitoring to avoid hyperoxia. Deferred cord clamping (≥60 sec), strict thermal regulation and skin-to-skin contact are strongly encouraged. Laryngeal mask airways can be used as an alternate device in failed bag-mask ventilation in term infants. The 2025 guidelines shift neonatal resuscitation from an algorithmic event to a continuum of care, emphasizing system readiness, team integration, precise physiological targets and structured recovery - while maintaining core resuscitation principles established in 2015.

Testicular torsion causes a compartment syndrome physiology in which detorsion alone may fail to restore perfusion because intratesticular pressure remains elevated after untwisting. This report describes a simple intraoperative adjunct practised by the author in a district hospital setting in Zambia: multiple needle punctures of the tunica albuginea immediately after detorsion, without formal fasciotomy or tunica vaginalis flap. The technique decompresses the intratesticular compartment, releases congested venous blood and allows clinical grading of testicular viability by the colour and speed of bleeding from the puncture sites. It requires no equipment beyond a standard needle, adds less than two minutes to the procedure and avoids the complexity of formal fasciotomy. The colour grading system derived from needle puncture response is described, and the physiological basis of the technique is outlined. Prospective documentation is encouraged.

Traditionally, tropical medicine has been concerned with infectious diseases in terms of diagnosis, treatment, prevention, and control. But there is a growing dual burden of communicable and non-communicable diseases in many low- and middle-income countries due to commercial determinants of health (CDoH). The marketing and availability of tobacco, alcohol, sugared drinks, and ultra-processed foods impact on health behaviour and lead to obesity, diabetes, heart disease, cancer, and poor infection outcomes. Hence, tropical medicine needs to move beyond the clinical realm to include consideration of the commercial context of disease. This requires healthcare practitioners, universities, scientific societies, and medical publications to promote informed regulation of commercial determinants, healthy food environments, taxation policy, health literacy, and protection from harmful commercial activity. It is vital that CDoH be incorporated into research, teaching and health promotion activities as an integral part of the preventive mandate of tropical medicine.

One-fifth of rabies cases may present with features of acute-onset flaccid paralysis, which mimic Guillain-Barré syndrome (GBS). Diagnosing paralytic rabies is challenging as the hallmark features such as aerophobia or hydrophobia tend to be absent in almost half of cases.

Alcohol use contributes substantially to global morbidity and mortality, necessitating reliable biomarkers for detection and monitoring. Existing biomarkers, including indirect markers and direct markers, have important limitations related to specificity, sensitivity and temporal detection windows. As a biomarker, creatine kinase (CK) demonstrates strong biological plausibility, as alcohol exerts direct and indirect myotoxic effects through oxidative stress, impaired protein synthesis and metabolic disruption, leading to muscle injury and enzyme leakage. However, its diagnostic specificity is also limited, as CK elevation can result from multiple non-alcohol-related conditions, including trauma, seizures and metabolic disturbances. Despite these limitations, CK shows clinical utility in identifying complications such as rhabdomyolysis, severe withdrawal states and risk of acute kidney injury. It correlates with withdrawal severity and may aid in risk stratification. Overall, CK is best positioned as a supplementary biomarker reflecting alcohol-related complications rather than a primary indicator of alcohol consumption.

Acute febrile illnesses in pregnant women living in sanitation-compromised regions of the Global South present overlapping symptoms of dengue, typhoid, and malaria, frequently causing severe maternal anemia, thrombocytopenia, and pregnancy loss. Peripheral frontline clinics often default to toxic, multi-class antimicrobial over-prescriptions owing to the absence of rapid differential tools. A streamlined syndromic triage framework is vital to rationalize care and improve outcomes.