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Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. [JOURNAL ARTICLE]
Nat Cell Biol 2009 Oct 18.
Abstract | Full Citation | | Ledesma FC, El Khamisy SF, Zuma MC, et al.
A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage. [Journal Article, Research Support, Non-U.S. Gov't]
Nature 2009 Oct 1; 461(7264):674-8.
Abstract | Full Citation | Find Related Articles | | Rocha-Muñoz AD, González-López L, Peguero-Gómez R, et al.
[Assessment of serum lgG activity correlation against anti-cyclic citrullinated peptide antibodies, anti-topoisomerase I and centromere proteins in Mexican patients with progressive systemic sclerosis] [English Abstract, Journal Article]
Rev Alerg Mex 2009 Jul-Aug; 56(4):103-7.
Abstract | Full Citation | Find Related Articles | | Yang Z, Carey JF, Champoux JJ
Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA. [JOURNAL ARTICLE]
FEBS J 2009 Sep 9.
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Topo IIIalpha and BLM act within the Fanconi anemia pathway in response to DNA-crosslinking agents. [Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't]
Cytogenet Genome Res 2009; 125(3):165-75.
Abstract | Full Citation | Find Related Articles | | Dalla Via L, Magno SM, Gia O, et al.
Benzothiopyranoindole-based antiproliferative agents: synthesis, cytotoxicity, nucleic acids interaction, and topoisomerases inhibition properties. [Journal Article, Research Support, Non-U.S. Gov't]
J Med Chem 2009 Sep 10; 52(17):5429-41.
Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Wesolowski R, Lee C, Kim R
Is there a role for second-line chemotherapy in advanced gastric cancer? [Journal Article]
Lancet Oncol 2009 Sep; 10(9):903-12.
Abstract | Full Citation | Find Related Articles | | You QD, Li ZY, Huang CH, et al.
Discovery of a Novel Series of Quinolone and Naphthyridine Derivatives as Potential Topoisomerase I Inhibitors by Scaffold Modification. [JOURNAL ARTICLE]
J Med Chem 2009 Aug 28.
Abstract | Full Citation | Publisher Full Text | Find Related Articles | | Bar FM, Khanfar MA, Elnagar AY, et al.
Rational Design and Semisynthesis of Betulinic Acid Analogues as Potent Topoisomerase Inhibitors. [JOURNAL ARTICLE]
J Nat Prod 2009 Aug 19.
Abstract | Full Citation | Find Related Articles | | Lin CP, Ban Y, Lyu YL, et al.
Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double-strand breaks at arrested replication forks. [JOURNAL ARTICLE]
J Biol Chem 2009 Aug 6.
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