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Methapyrilene journal articles from PubMed MEDLINE database

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Mercer AE, Regan SL, Hirst CM, et al. 
Functional and toxicological consequences of metabolic bioactivation of methapyrilene via thiophene S-oxidation: induction of cell defence, apoptosis and hepatic necrosis. [JOURNAL ARTICLE]
Toxicol Appl Pharmacol 2009 Jun 9.
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Schug M, Heise T, Bauer A, et al. 
Primary rat hepatocytes as in vitro system for gene expression studies: comparison of sandwich, Matrigel and 2D cultures. [JOURNAL ARTICLE]
Arch Toxicol 2008 Nov 6.
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Uehara T, Hirode M, Ono A, et al. 
A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats. [Journal Article, Research Support, Non-U.S. Gov't]
Toxicology 2008 Aug 19; 250(1):15-26.
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Graham EE, Walsh RJ, Hirst CM, et al. 
Identification of the thiophene ring of methapyrilene as a novel bioactivation-dependent hepatic toxicophore. [Journal Article, Research Support, Non-U.S. Gov't]
J Pharmacol Exp Ther 2008 Aug; 326(2):657-71.
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Uehara T, Kiyosawa N, Hirode M, et al. 
Gene expression profiling of methapyrilene-induced hepatotoxicity in rat. [Journal Article]
J Toxicol Sci 2008 Feb; 33(1):37-50.
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Auman JT, Chou J, Gerrish K, et al. 
Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue. [Journal Article]
Environ Health Perspect 2007 Apr; 115(4):572-8.
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Craig A, Sidaway J, Holmes E, et al. 
Systems Toxicology: Integrated Genomic, Proteomic and Metabonomic Analysis of Methapyrilene Induced Hepatotoxicity in the Rat. [JOURNAL ARTICLE]
J Proteome Res 2006 Jul 7; 5(7):1586-1601.
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Beekman JM, Boess F, Hildebrand H, et al. 
Gene expression analysis of the hepatotoxicant methapyrilene in primary rat hepatocytes: an interlaboratory study. [Journal Article]
Environ Health Perspect 2006 Jan; 114(1):92-9.
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Goodsaid FM, Smith RJ, Rosenblum IY 
Quantitative PCR deconstruction of discrepancies between results reported by different hybridization platforms. [Evaluation Studies, Journal Article]
Environ Health Perspect 2004 Mar; 112(4):456-60.
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Chu TM, Deng S, Wolfinger R, et al. 
Cross-site comparison of gene expression data reveals high similarity. [Evaluation Studies, Journal Article]
Environ Health Perspect 2004 Mar; 112(4):449-55.
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