| Title | Retrospective study of bitolterol mesylate in the treatment of conditions associated with reversible bronchospasm. |
| Author(s) | Messina MS |
| Institution | St. Luke's Hospital, New Bedford, Massachusetts, USA. |
| Source | Adv Ther 1995 May-Jun; 12(3):157-63. |
| MeSH | Administration, Inhalation
Aged
Bronchial Spasm
Bronchodilator Agents
Ethanolamines
Female
Humans
Male
Middle Aged
Nebulizers and Vaporizers
Respiratory Function Tests
Retrospective Studies
|
| Abstract | Patients with reversible bronchospasm benefit from the use of inhaled beta-adrenergic agents. In this retrospective study of 24 older patients with a variety of conditions associated with reversible bronchospasm--asthma, asthma with emphysema, chronic bronchitis, and asthmatic bronchitis--symptomatic improvement was noted after treatment with inhaled bitolterol mesylate. Symptoms resolved or improved after 1 month in 93.8% (15/16) of patients using a metered-dose inhaler and in 75% (6/8) of those using a hand-held nebulizer. Sixteen additional patients were randomly selected to undergo pulmonary function tests after receiving two to three puffs of bitolterol from a metered-dose inhaler. FEV1 improved by 10.9%, FVC by 12.1%, and FEF25%-75% by 34.4% after administration of bitolterol. No adverse events were noted in any patients in either group. The results of this retrospective study suggest that bitolterol is an effective and safe treatment in patients with conditions associated with reversible bronchospasm. |
| Language | eng |
| Pub Type(s) | Case Reports
Journal Article
|
| PubMed ID | 10155050 |
