| Title | Measles immunization in HIV-infected children. American Academy of Pediatrics. Committee on Infectious Diseases and Committee on Pediatric AIDS. | | Source | Pediatrics 1999 May; 103(5 Pt 1):1057-60. | | MeSH | Adolescent
Adult
CD4 Lymphocyte Count
Child
Child, Preschool
HIV Infections
Health Policy
Humans
Infant
Infant, Newborn
Measles
Measles Vaccine
Measles-Mumps-Rubella Vaccine
Mumps Vaccine
Pneumonia, Viral
Rubella Vaccine
United States
Vaccines, Combined
| | Abstract | Children infected with human immunodeficiency virus (HIV) have had high rates of mortality attributable to measles, but until recently, measles vaccine was assumed to be safe for these children. A single fatal case of pneumonia attributable to vaccine type-measles virus has been documented in a young adult with acquired immunodeficiency syndrome. Because a protective immune response often does not develop in severely immunocompromised HIV-infected patients after immunization and some risk of severe complications exists, HIV-infected children, adolescents, and young adults who are severely immunocompromised (based on age-specific CD4 lymphocyte enumeration) attributable to HIV infection should not receive measles vaccine. All other HIV-infected children, adolescents, and young adults who are not severely immunocompromised should receive measles-mumps-rubella vaccine. | | Language | eng | | Pub Type(s) | Guideline
Journal Article
Practice Guideline
| | PubMed ID | 10224192 |
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