Longstanding trigeminal sensory neuropathy of nontraumatic cause. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. [Oral Surg Oral Med Oral Pathol Oral Radiol Endod] Journal article

Title	Longstanding trigeminal sensory neuropathy of nontraumatic cause.
Author(s)	Shotts RH, Porter SR, Kumar N, Scully C
Institution	Department of Oral Medicine, Eastman Dental Institute of Oral Health Care Sciences, University of London, United Kingdom.
Source	Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999 May; 87(5):572-6.
MeSH	Adenocarcinoma Adult Aged Breast Neoplasms Carcinoma Cerebellar Neoplasms Chronic Disease Connective Tissue Diseases Cranial Nerve Diseases Female Glioblastoma Humans Intracranial Arteriosclerosis Lung Neoplasms Male Middle Aged Paresthesia Prostatic Neoplasms Retrospective Studies Trigeminal Nerve
Abstract	OBJECTIVE: Trigeminal sensory neuropathy is an uncommon but often significant orofacial symptom. There are few detailed descriptions of the problem in the dental literature. The aim of this study was to evaluate the clinical presentation and management of a cohort of patients presenting with anesthesia/paresthesia affecting one or more divisions of the trigeminal nerve unrelated to any identifiable traumatic cause. STUDY DESIGN: Nine patients with trigeminal neuropathy were examined. Each patient underwent a standard protocol of examination and hematologic, serologic, radiologic, and histopathologic investigations, as appropriate. RESULTS: Trigeminal neuropathy was found to be secondary to distant malignancy in 4 patients and to connective tissue disease in 2 patients. In each of 3 other patients, there was no obvious cause for the neuropathy. Patients with malignancy as the cause of their neuropathy tended to have involvement of more than one division of the trigeminal nerve and/or other neurologic features. CONCLUSIONS: Trigeminal sensory neuropathy may herald underlying distant malignancy or connective tissue disease. Anesthesia and paresthesia of the orofacial region are therefore serious clinical symptoms that must be carefully investigated before a diagnosis of idiopathic disease is made.
Language	eng
Pub Type(s)	Journal Article
PubMed ID	10348515

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