| Title | [Toxoplasmosis IgG avidity: what importance does it have in pregnancy?] | | Author(s) | Suter BJ, Blatter S, Bittar M, Viollier EH | | Institution | Institut Dr. Viollier, Basel. | | Source | Schweiz Med Wochenschr 1999 Dec 11; 129(49):1938-41. | | MeSH | Animals
Antibodies, Protozoan
Antibody Affinity
Antigens, Protozoan
English Abstract
Female
Humans
Immunoglobulin G
Immunoglobulin M
Pregnancy
Pregnancy Complications, Parasitic
Toxoplasma
Toxoplasmosis
| | Abstract | Avidity describes the binding strength of specific antibody to antigen. It was found to be low in the first phase after primary infection but then to increase over time. In addition to classic serodiagnosis of toxoplasmosis, measurement of avidity provides information making it possible to distinguish between acute and chronic infection and is of particular interest in pregnant women. In 229 women we found IgG and IgM antibodies suggestive of acute infection. A total of 188 (82%) had an avidity index > 0.3, indicating that the infection had occurred at least four months earlier. Based on this additional information, repeated testing and unnecessary anxiety can be avoided. | | Language | ger | | Pub Type(s) | Journal Article
| | PubMed ID | 10635088 |
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