| Title | Comparative anti-dandruff efficacy between a tar and a non-tar shampoo. |
| Author(s) | Piérard-Franchimont C, Piérard GE, Vroome V, Lin GC, Appa Y |
| Institution | Department of Dermatopathology, University of Liège, Belgium. |
| Source | Dermatology 2000; 200(2):181-4. |
| MeSH | Adult
Coal Tar
Comparative Study
Double-Blind Method
Hair Preparations
Humans
Keratolytic Agents
Malassezia
Male
Scalp Dermatoses
|
| Abstract | A randomized double-blind clinical study was conducted on two groups of 30 volunteers using either a non-tar shampoo (2% salicylic acid, 0.75% piroctone olamine and 0.5% elubiol) or a 0.5% coal tar shampoo. Subjects were diagnosed as having moderate to marked dandruff. The study consisted of a 3-week washout, followed by a 4-week treatment and a 4-week posttreatment regression phase. The clinical evaluations and subject self-assessments showed that the non-tar shampoo was as effective as the tar shampoo. Both received high approval ratings (> or =70%). Biometrological methods proved to be more sensitive than clinical evaluations to assess the efficacy of the shampoos. The non-tar shampoo yielded a significantly better reduction of Malassezia spp. counts (p<0.02) during the treatment phase and reduced the spontaneous increase in squamometry values (p< 0.01) during the posttreatment phase. It is concluded that a formulation associating salicylic acid, piroctone olamine and elubiol exhibited increased beneficial effects compared to the coal tar shampoo. |
| Language | eng |
| Pub Type(s) | Clinical Trial
Journal Article
Randomized Controlled Trial
|
| PubMed ID | 10773717 |
