Chronic ergot toxicity: A rare cause of lower extremity ischemia. Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. [J Vasc Surg] Journal article

Title	Chronic ergot toxicity: A rare cause of lower extremity ischemia.
Author(s)	Garcia GD, Goff JM, Hadro NC, O'donnell SD, Greatorex PS
Institution	Department of Surgery, Womack Army Medical Center, Ft Bragg, NC, USA.
Source	J Vasc Surg 2000 Jun; 31(6):1245-7.
MeSH	Adult Caffeine Chronic Disease Cyclizine Drug Combinations Ergotamine Ergotism Female Foot Ulcer Humans Intermittent Claudication Ischemia Leg Migraine Disorders Platelet Aggregation Inhibitors
Abstract	Chronic ergot toxicity is a rare cause of lower extremity ischemia. The cornerstone of therapy in ergot toxicity is to discontinue the use of caffeine, cigarettes, and all ergot-containing medications. Although multiple different therapies have been recommended for acute toxicity, no specific treatment is uniformly recommended in chronic toxicity. We present a case of long-term ergot use for migraine headaches in a woman who had severe chronic lower extremity claudication. This case demonstrates the unique features associated with the diagnosis and management of chronic ergot toxicity. We recommend a conservative approach consisting of observation, antiplatelet agents, and the discontinuance of ergots. If symptoms progress to rest pain or gangrene, surgical treatment should be considered.
Language	eng
Pub Type(s)	Case Reports Journal Article
PubMed ID	10842162

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