| Title | Delayed generalized allergic reactions to corticosteroids. |
| Author(s) | Bircher AJ, Bigliardi P, Zaugg T, Mäkinen-Kiljunen S |
| Institution | Allergy Clinic, Department of Dermatology, University Hospital Basel, Switzerland. Andreas.Bircher@unibas.ch |
| Source | Dermatology 2000; 200(4):349-51. |
| MeSH | Adrenal Cortex Hormones
Adult
Asthma
Budesonide
Dermatitis
Drug Eruptions
Humans
Hypersensitivity, Delayed
Male
Patch Tests
Prednisolone
Skin
|
| Abstract | A 37-year-old patient presented with a severe allergic local reaction upon inhalation of budesonide for asthma. Skin tests were positive for budesonide and amcinonide (group B) and elicited a strong local reaction and a disseminated macular exanthema. Corticosteroids from other groups were well tolerated. A 38-year-old male patient had first an allergic contact dermatitis to topically applied prednisolone acetate and then a disseminated eczematous exanthema upon oral intake of prednisone. A delayed-type sensitization to corticosteroids from group A such as hydrocortisone, prednisone and tixocortol pivalate was identified. A detailed diagnosis in patients with allergic reactions to corticosteroids is crucial with regard to their use in emergency therapy. |
| Language | eng |
| Pub Type(s) | Case Reports
Journal Article
|
| PubMed ID | 10894975 |
