Acute renal vein thrombosis, oral contraceptive use, and hyperhomocysteinemia. Mayo Clinic proceedings. Mayo Clinic [Mayo Clin Proc] Journal article | | Title | Acute renal vein thrombosis, oral contraceptive use, and hyperhomocysteinemia. | | Author(s) | Chan HH, Douketis JD, Nowaczyk MJ | | Institution | Department of Medicine, McMaster University, Hamilton, Ontario, Canada. | | Source | Mayo Clin Proc 2001 Feb; 76(2):212-4. | | MeSH | Acute Disease Adult Contraceptives, Oral Female Humans Hyperhomocysteinemia Renal Veins Risk Factors Venous Thrombosis
| | Abstract | Oral contraceptive use and hyperhomocysteinemia are considered to be relatively weak risk factors for venous thromboembolism. We report a case of acute renal vein thrombosis, a rare and aggressive form of thromboembolism, that occurred in a 21-year-old woman taking oral contraceptives, who was subsequently found to have marked hyperhomocysteinemia. This case suggests that the oral contraceptive and hyperhomocysteinemia may interact in a synergistic manner in the pathogenesis of thrombosis. In oral contraceptive users who develop venous thrombosis in the absence of other risk factors, clinicians should consider investigations for an underlying prothrombotic biochemical disorder. | | Language | eng | | Pub Type(s) | Case Reports Journal Article
| | PubMed ID | 11213312 |
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