| Title | Learning impairment is associated with recall ability in multiple sclerosis. | | Author(s) | Demaree HA, Gaudino EA, DeLuca J, Ricker JH | | Institution | Kessler Medical Rehabilitation Research and Education Corporation, Neuropsychology and Neuroscience Laboratory, West Orange, New Jersey, USA. | | Source | J Clin Exp Neuropsychol 2000 Dec; 22(6):865-73. | | MeSH | Adult
Cognition
Face
Female
Humans
Learning Disorders
Male
Memory
Mental Recall
Middle Aged
Multiple Sclerosis
Neuropsychological Tests
Paired-Associate Learning
Research Support, Non-U.S. Gov't
Space Perception
Verbal Learning
| | Abstract | Recent evidence suggests that persons with multiple sclerosis may experience deficits in verbal and visuospatial acquisition rather than recall. The present study was designed to determine whether this finding generalized to a broader range of neuropsychological tests of learning and memory. To control for group differences in information acquisition, healthy controls (HCs) and persons with multiple sclerosis (MS) were trained to specific learning criteria on both verbal (i.e., paragraph learning and paired associates) and visuospatial (i.e., facial recognition) memory tasks. Persons with MS required significantly more learning trials to meet criteria on the paragraph learning and facial recognition tasks, but not the paired associates test. However, after learning comparable amounts of information, the MS and HC groups recalled statistically similar amounts of information at 30-minutes, 90-minutes, and up to 1-week on the paragraph learning and paired associate tests. This suggests that persons with MS may have deficits in acquisition rather than recall per se. Results are discussed in terms of possible rehabilitation strategies to improve memory functioning in persons with MS. | | Language | eng | | Pub Type(s) | Clinical Trial
Journal Article
| | PubMed ID | 11320441 |
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