Spontaneous regression of hepatic adenoma in a patient with glycogen storage disease type I after hemodialysis: ultrasonographic and CT findings. Internal medicine (Tokyo, Japan) [Intern Med] Journal article

Title	Spontaneous regression of hepatic adenoma in a patient with glycogen storage disease type I after hemodialysis: ultrasonographic and CT findings.
Author(s)	Iijima H, Moriwaki Y, Yamamoto T, Takahashi S, Nishigami T, Hada T
Institution	Third Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya.
Source	Intern Med 2001 Sep; 40(9):891-5.
MeSH	Adenoma, Liver Cell Adult Biopsy Female Glycogen Storage Disease Type I Humans Kidney Failure Liver Liver Neoplasms Neoplasm Regression, Spontaneous Renal Dialysis Tomography, X-Ray Computed
Abstract	A 23-year-old woman was admitted to our hospital with recurrent gouty arthritis. Laboratory findings showed hypoglycemia, lactic acidosis, hyperlipidemia, and hyperuricemia, with normal values of serum alfa-fetoprotein (AFP) and protein induced by vitamin K absence (PIVKA-II). A diagnosis of glycogen storage disease type I (GSD-type I) was made on the basis of the laboratory data, liver biopsy findings, and partially deficient thrombocyte glucose-6-phosphatase (G-6-Pase) activity. Ultrasonography and computed tomography revealed multiple focal hepatic masses. Biopsied specimens of the lesion demonstrated a hepatic adenoma, which changed in appearance in the relatively short period between echography and computed tomography. This interesting phenomenon may highlight the importance for careful follow-up of hepatic adenomas, because of the potential of rupture, hemorrhage, or malignant transformation. During follow-up, the present patient received hemodialysis due to renal failure, and the adenoma regressed spontaneously after 8 years. Included are diagnostic images, demonstrating the association of hepatic adenoma and GSD-type I.
Language	eng
Pub Type(s)	Case Reports Journal Article
PubMed ID	11579951

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