Sentra, a database of signal transduction proteins. Nucleic acids research. [Nucleic Acids Res] Journal article

Sentra (http://www-wit.mcs.anl.gov/sentra) is a database of signal transduction proteins with the emphasis on microbial signal transduction. The database was updated to include classes of signal transduction systems modulated by either phosphorylation or methylation reactions such as PAS proteins and serine/threonine kinases, as well as the classical two-component histidine kinases and methyl-accepting chemotaxis proteins. Currently, Sentra contains signal transduction proteins from 43 completely sequenced prokaryotic genomes as well as sequences from SWISS-PROT and TrEMBL. Signal transduction proteins are annotated with information describing conserved domains, paralogous and orthologous sequences, and conserved chromosomal gene clusters. The newly developed user interface supports flexible search capabilities and extensive visualization of the data.

Nucleic acids research. [Nucleic Acids Res]

Chemotaxis
Computer Graphics
Conserved Sequence
Databases, Protein
Genome
Information Storage and Retrieval
Internet
Methylation
Multigene Family
Phosphorylation
Prokaryotic Cells
Protein Kinases
Protein Structure, Tertiary
Protein-Serine-Threonine Kinases
Proteins
Research Support, U.S. Gov't, Non-P.H.S.
Sequence Homology
Signal Transduction