A pilot investigation to subjectively measure treatment effect and side-effect profile of non-ablative skin remodeling using a 532 nm, 2 ms pulse-duration laser. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. [J Cosmet Laser Ther] Journal article | | Title | A pilot investigation to subjectively measure treatment effect and side-effect profile of non-ablative skin remodeling using a 532 nm, 2 ms pulse-duration laser. | | Author(s) | Bernstein EF, Ferreira M, Anderson D | | Institution | Laser Surgery and Cosmetic Dermatology Centers, Marlton, NJ, USA. dermguy@hotmail.com | | Source | J Cosmet Laser Ther 2001 Sep; 3(3):137-41. | | MeSH | Acne Vulgaris
Adult
Cicatrix
Face
Female
Humans
Laser Surgery
Middle Aged
Patient Satisfaction
Pilot Projects
Reconstructive Surgical Procedures
Skin
Skin Aging
Treatment Outcome
| | Abstract | BACKGROUND AND
OBJECTIVE: Carbon dioxide laser skin resurfacing has become a standard treatment for wrinkles and sun-damaged skin. This ablative treatment, however, is associated with undesirable complications and long recovery times. A growing body of evidence suggests that dermal inflammation and subsequent collagen formation can be stimulated without removal of the epidermis, raising the possibility of effective non-ablative skin remodeling for mild to moderately photodamaged skin.
MATERIALS AND METHODS: This preliminary study was performed to evaluate the safety and subject satisfaction of non-ablative skin remodeling using a 532 nm, 2 ms pulse-duration, frequency-doubled Nd:YAG laser. Subjects with mild-to-deep lip wrinkles and mild-moderate acne scarring were treated one half of their lip (wrinkles) or cheek (acne scarring), leaving the other side as an untreated control. Subjects were treated at 3-6 week intervals for an average of three treatments. Subjective assessment of improvement was estimated by subject self-evaluation of the percentage improvement over baseline, and a blinded observer attempted to identify the treated side on physical examination.
RESULTS: Subjective assessment revealed an average improvement of 51.4% and 53.6% for upper lip wrinkles and facial acne scarring, respectively. Side effects were limited to transient erythema that resolved over 0.25-2 hours following treatment.
CONCLUSIONS: These results demonstrate that non-ablative treatment with the 532 nm, 2 ms pulse-duration Nd:YAG laser results in subjective improvement of rhytides and acne scarring, with a high safety profile. | | Language | eng | | Pub Type(s) | Clinical Trial
Journal Article
Randomized Controlled Trial
| | PubMed ID | 12006190 |
|
|
| |
Advertise on this site.
| | |
|
