| Title | Iontophoretically applied lidocaine and the prevention of pain associated with the injection of intravenous propofol: a comparison with intravenous lidocaine. |
| Author(s) | Sharpe P, Asif M, Victoria A, Rowbotham DJ |
| Institution | University of Leicester, Department of Anaesthesia, UK. ps46@le.ac.uk |
| Source | Eur J Anaesthesiol 2002 Mar; 19(3):170-2. |
| MeSH | Adolescent
Adult
Aged
Anesthetics, Intravenous
Anesthetics, Local
Comparative Study
Double-Blind Method
Female
Humans
Injections, Intravenous
Iontophoresis
Lidocaine
Male
Middle Aged
Pain
Pain Measurement
Propofol
Prospective Studies
|
| Abstract | BACKGROUND AND
OBJECTIVE: Pain following the injection of propofol is a common problem. It is often treated by the coadministration of intravenous lidocaine. Iontophoresis, which facilitates the delivery of charged molecules such as lidocaine to body tissues, may be a practical alternative to lessen the pain.
METHODS: The iontophoretic application of lidocaine was compared with intravenous lidocaine to assess the relative efficacy of reducing pain during propofol administration.
RESULTS: The incidence rate of moderate or severe pain was significantly greater in the iontophoresis group (26.7 compared with 6.9% in the intravenous lidocaine group) (P < 0.05).
CONCLUSIONS: The iontophoretic administration of lidocaine 60 mg does not compare favourably with lidocaine 40 mg mixed with propofol for the reduction of pain on administration of propofol. |
| Language | eng |
| Pub Type(s) | Clinical Trial
Journal Article
Randomized Controlled Trial
|
| PubMed ID | 12071235 |
