The precursors of malignant melanoma. Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer. [Recent Results Cancer Res] Journal article

Title	The precursors of malignant melanoma.
Author(s)	Crowson AN, Magro CM, Sanchez-Carpintero I, Mihm MC
Source	Recent Results Cancer Res 2002.:75-84.
MeSH	Cell Transformation, Neoplastic Dysplastic Nevus Syndrome Humans Hutchinson's Melanotic Freckle Melanoma Precancerous Conditions Skin Neoplasms
Abstract	The precursors to melanoma are generally considered to be related to nevi of different types. Here we emphasize the dysplastic nevus, the congenital nevus, and lentigo maligna as specific lesions. The dysplastic nevus is discussed not only as a formal precursor but also as a marker of cutaneous melanoma. The clinical and histologic characteristics are outlined, as well as evidence of progression in dysplastic nevi. The congenital nevus is briefly reviewed and emphasis is placed upon clues to malignant degeneration. The concept of lentigo maligna as a precursor as distinct from an in situ phase is detailed.
Language	eng
Pub Type(s)	Journal Article Review
PubMed ID	12079242

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