| Title | Effect of ligand structure on the zinc-catalyzed Henry reaction. Asymmetric syntheses of (-)-denopamine and (-)-arbutamine. | | Author(s) | Trost BM, Yeh VS, Ito H, Bremeyer N | | Institution | Department of Chemistry, Stanford University, California 94305-5080, USA. bmtrost@stanford.edu | | Source | Org Lett 2002 Aug 8; 4(16):2621-3. | | MeSH | Catecholamines
Ethanolamines
Ligands
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Zinc
| | Abstract | [reaction: see text] Syntheses of variously modified ligands for the dinuclear zinc catalysts for the asymmetric aldol and nitroaldol (Henry) reactions are reported. Catalytic enantioselective nitroaldol reactions promoted by these modified ligands led to efficient syntheses of the beta-receptor agonists (-)-denopamine and (-)-arbutamine. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 12153193 |
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