Clauss SB, Manco-Johnson MJ, Quivers E, Takemoto C, Spevak PJ Primary antiphospholipid antibody syndrome and cardiac involvement in a child. [Case Reports, Journal Article] Pediatr Cardiol 2003 May-Jun; 24(3):292-4.
We report a case of polyvalvar disease and recurrent thrombosis in a 2-year-old boy due to primary antiphospholipid antibody syndrome. His diagnosis was delayed, and he was treated for other diagnoses, including culture-negative endocarditis. Primary antiphospholipid antibody syndrome is rarely discussed in the pediatric cardiology literature, and this case highlights the need for early diagnosis to prevent recurrent valve dysfunction and thrombosis.
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