| Title | Haematological problems in pregnancy. | | Author(s) | Burrows RF | | Institution | Maternal-fetal medicine, Monash University, Clayton, Australia. robert.burrows@med.monash.edu.au | | Source | Curr Opin Obstet Gynecol 2003 Apr; 15(2):85-90. | | MeSH | Anemia
Erythropoietin
Female
Heparin
Humans
Iron, Dietary
Pregnancy
Pregnancy Complications, Hematologic
Prenatal Care
Prenatal Diagnosis
Randomized Controlled Trials
Thrombocytopenia
Thromboembolism
| | Abstract | PURPOSE OF REVIEW: Haematological disorders of pregnancy are common reasons for referral. It is reasonable then to devote a review to recent publications on these issues.
RECENT FINDINGS: Several narrative reviews on the management of venous thromboembolic disease in pregnancy provide exceptional guidance. They highlight, however, that most of what is done is still based on opinions from highly qualified people, extrapolated from the non-pregnant literature but not involving randomized trials on pregnant patients. It is apparent that a consensus is nearing on the management of both pregnancy-related thrombocytopenia and idiopathic (immune) thrombocytopenic purpura. Several randomized controlled trials are reported on the treatment of non-deficiency anaemia, using oral iron, intravenous iron and erythropoietin, which contribute to the debate on the appropriate and best intervention for this common problematic issue.
SUMMARY: This review demonstrates the need for appropriately sized randomized trials on haematological issues in pregnancy. With heparin becoming the most common medication being administered prophylactically and therapeutically in pregnancy, it is important that quality trials are performed to guide its sensible utilization. | | Language | eng | | Pub Type(s) | Journal Article
Review
| | PubMed ID | 12634598 |
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