Jejunal inhibition of pentagastrin-induced gastric acid secretion in man and Heidenhain pouch dogs. Scandinavian journal of gastroenterology [Scand J Gastroenterol] Journal article

Title	Jejunal inhibition of pentagastrin-induced gastric acid secretion in man and Heidenhain pouch dogs.
Author(s)	Christiansen J, Holst JJ, Rokkjaer M
Source	Scand J Gastroenterol 1976; 11(2):219-24.
MeSH	Adult Animals Dogs Female Gastric Juice Gastric Mucosa Glucose Humans Injections Jejunum Male Pentagastrin Saline Solution, Hypertonic Secretory Rate Sodium Chloride
Abstract	The administration of hypertonic glucose and saline and of fat intrajejunally in man caused a marked and almost identical inhibition of pentagastrin-stimulated gastric acid secretion. Hypertonic glucose administered intrajejunally in Heidenhain pouch dogs resulted in an equal inhibition of pentagastrin-induced acid secretion from the pouch and the main stomach, whereas hypertonic saline had no effect. The study demonstrates the existence of potent jejunal inhibitors of gastric secretion, which seem to operate independently of vagal innervation.
Language	eng
Pub Type(s)	Journal Article
PubMed ID	1265443

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