| Title | Moricizine induced increase in pacing threshold. | | Author(s) | Girod JP, Marrouche N, Chen MS, Natale A | | Institution | Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave., Desk F-15, Cleveland, OH 44195, USA. | | Source | Pacing Clin Electrophysiol 2003 Jan; 26(1 Pt 1):110-1. | | MeSH | Aged
Anti-Arrhythmia Agents
Electrocardiography
Female
Heart Conduction System
Humans
Moricizine
Pacemaker, Artificial
Tachycardia, Ventricular
| | Abstract | A 72-year-old woman who was experiencing incessant ventricular tachycardia and recurrent automatic implantable cardioverter defibrillator (AICD) firing despite amiodarone therapy was referred to the Cleveland Clinic Foundation. Myocardial ischemia and infarction were ruled out by standard means. Several antiarrhythmic medications were tried previously without success. Moricizine, 200 mg three times daily, was initiated and controlled the ventricular tachycardia. However, after the dose of moricizine was titrated upward, the patient became symptomatically bradycardic and the ECG exhibited 2:1 block of her paced rhythm and an increased ventricular pacing threshold. | | Language | eng | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 12685150 |
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