| Title | Granulomatous mammary disease: ten years' experience with fine needle aspiration cytology. | | Author(s) | Elsiddig KE, Khalil EA, Elhag IA, Elsafi ME, Suleiman GM, Elkhidir IM, Hussein AM, El-Hassan AM | | Institution | Department of Surgery, Faculty of Medicine, Khartoum, Sudan. | | Source | Int J Tuberc Lung Dis 2003 Apr; 7(4):365-9. | | MeSH | Adult
Antitubercular Agents
Biopsy, Needle
Chronic Disease
Cytodiagnosis
Female
Granuloma
Humans
Incidence
Mastitis
Mycobacterium tuberculosis
Prognosis
Risk Factors
Sensitivity and Specificity
Severity of Illness Index
Sudan
| | Abstract | OBJECTIVE: To determine the aetiological types of granulomatous disease of the breast in women presenting with mammary complaints in the Sudan.
METHODS: Clinical history and physical examination, complete blood counts, Mantoux test, histopathology and fine needle aspiration cytology (FNAC).
RESULTS: Granulomatous mastitis was seen in 11/2500 (0.44%) patients with mammary disease over a 10-year period. All were of childbearing age (mean 26.0 +/- 5.9 years). Common presentations were diffuse swelling, well-circumscribed masses, nipple retraction, multiple sinuses and superficial skin ulcers. Lymphadenopathy was seen in more than 60% of the patients. Diagnosis was based on cytomorphological features in 10/11 cases and histopathology in one. Nine were diagnosed with tuberculous mastitis and two with idiopathic granulomatous mastitis. Acid-fast bacilli (AFB) could not be demonstrated in any of the cytology smears. Tuberculous mastitis responded to empirical anti-tuberculosis treatment, with a minimum follow-up of 2 years in seven women.
CONCLUSION: Tuberculous mastitis is a rare entity in women with mammary disease in the Sudan. Alternative diagnoses such as idiopathic granulomatous mastitis should be made only after failure of an adequate trial of anti-tuberculosis treatment. FNAC is a useful diagnostic tool even if AFB cannot be demonstrated. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 12729342 |
|
