| Title | [Vitamin K deficiency bleeding in an infant despite adequate prophylaxis] | | Author(s) | van Hasselt PM, Houwen RH, van Dijk AT, de Koning TJ | | Institution | Wilhelmina Kinderziekenhuis, afd. Kindergeneeskunde, Lundlaan 6, 3584 EA Utrecht. p.vanhasselt@wkz.azu.nl | | Source | Ned Tijdschr Geneeskd 2003 Apr 19; 147(16):737-40. | | MeSH | Antifibrinolytic Agents
Breast Feeding
Cholestasis
English Abstract
Fatal Outcome
Female
Hemorrhagic Disease of Newborn
Humans
Infant
Infant, Newborn
Intracranial Hemorrhages
Lipid Metabolism, Inborn Errors
Vitamin K
Vitamin K Deficiency
| | Abstract | Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 micrograms the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had occurred. In an infant with a bleeding tendency, one should consider the possibility of vitamin K deficiency, even if adequate prophylaxis has been given. | | Language | dut | | Pub Type(s) | Case Reports
Comment
Journal Article
| | PubMed ID | 12731461 |
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