CNS cryptococcoma in an HIV-positive patient. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) [J Int Assoc Physicians AIDS Care (Chic Ill)] Journal article

Title	CNS cryptococcoma in an HIV-positive patient.
Author(s)	Troncoso A, Fumagalli J, Shinzato R, Gulotta H, Toller M, Bava J
Institution	University of Buenos Aires, Francisco J Muñiz Hospital, Buenos Aires, Argentina. alcidestr@hotmail.com
Source	J Int Assoc Physicians AIDS Care (Chic Ill) 2002 Oct-Dec; 1(4):131-3.
MeSH	AIDS-Related Opportunistic Infections Adult Amphotericin B Antifungal Agents Diagnosis, Differential Fluconazole HIV Infections Humans Magnetic Resonance Imaging Male Meningitis, Cryptococcal
Abstract	This is the first case of brain cryptococcoma in an AIDS patient reported in Argentina. The patient was a 28-year-old white heterosexual man with AIDS who presented with altered mental status, seizures, visual hallucinations, headache, and fever without significant focal neurological deficit. He had a lumbar puncture, and was treated for cryptococcal meningitis. Subsequent brain CT scanning and MRI disclosed a mass lesion in the occipital lobe. Histopathological examination of biopsy was compatible with cryptococcoma, and tissue culture revealed Cryptococcus neoformans. Resolution of the mass and edema resulted after treatment with intravenous amphotericin B for six weeks, which was followed with maintenance oral fluconazole. Intracranial mass is an uncommon complication in AIDS patients with cryptococcosis, and cryptococcoma should be considered as differential diagnosis of brain mass lesion in these patients. The etiologic diagnosis is necessary because central nervous system (CNS) toxoplasmosis, lymphoma, and tuberculoma can produce similar clinical syndromes and MRI or CT findings to cryptococcoma. Also, these pathologies may coexist with meningeal cryptococcosis.
Language	eng
Pub Type(s)	Case Reports Journal Article
PubMed ID	12942671

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