| Title | Efficacy of Arthrotec in the treatment of rheumatoid arthritis. | | Author(s) | Hannequin JR | | Institution | Civils Hospices, Strasbourg, France. | | Source | Scand J Rheumatol Suppl 1992.:7-14. | | MeSH | Administration, Oral
Adult
Aged
Aged, 80 and over
Arthritis, Rheumatoid
Comparative Study
Diclofenac
Dose-Response Relationship, Drug
Double-Blind Method
Drug Combinations
Female
Humans
Male
Middle Aged
Misoprostol
| | Abstract | In a double-blind study, 346 patients with active rheumatoid arthritis were randomly assigned to receive Arthrotec, a combination of 50 mg of diclofenac and 200 *g of misoprostol, or 50 mg of diclofenac; the drugs were given two or three times daily for 12 weeks. At weeks 4, 8, and 12 of treatment, no clinically significant differences between the two treatment groups were noted on measures of joint tenderness, pain, and swelling or on physicians' and patients' assessments of disease severity. | | Language | eng | | Pub Type(s) | Clinical Trial
Journal Article
Randomized Controlled Trial
| | PubMed ID | 1439627 |
|
