| Title | Management of acute cancer treatment-induced diarrhea. | | Author(s) | Stern J, Ippoliti C | | Institution | M. D. Anderson Cancer Center, University of Texas, Houston, TX, USA. | | Source | Semin Oncol Nurs 2003 Nov; 19(4 Suppl 3):11-6. | | MeSH | Antidiarrheals
Antineoplastic Combined Chemotherapy Protocols
Atropine
Diarrhea
Diphenoxylate
Humans
Loperamide
Neoplasms
Nurse's Role
Nurse-Patient Relations
Nursing Assessment
Nursing Methodology Research
Octreotide
Oncologic Nursing
Quality of Life
| | Abstract | OBJECTIVES: To describe the dietary and pharmacologic management of acute CTID.
DATA SOURCES: Primary and secondary literature, and clinical experience.
CONCLUSION: When dietary strategies do not work, or when patients present with grade 3/4 diarrhea, pharmacologic intervention is required. First-line therapy should be initiated quickly with loperamide or diphenoxylate/atropine in recommended doses. Somatostatin analogues are effective as second-line therapy or as first-line therapy for patients with grade 3/4 diarrhea.
IMPLICATIONS FOR NURSING PRACTICE: Oncology nurses should strive to match treatment with the severity of symptoms of CTID. Whatever therapy is chosen, the goal must be to quickly control this debilitating and potentially life-threatening side effect so that primary chemotherapy and/or radiation therapy may be resumed and completed. | | Language | eng | | Pub Type(s) | Journal Article
Review
| | PubMed ID | 14702928 |
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