| Title | Recurrence of primary renal disease on kidney graft: a European pediatric experience. | | Author(s) | Broyer M, Selwood N, Brunner F | | Institution | Department of Paediatric Nephrology, Necker-Enfants Malades Hospital, Paris, France. | | Source | J Am Soc Nephrol 1992 Jun; 2(12 Suppl):S255-7. | | MeSH | Adolescent
Child
Child, Preschool
Europe
Female
Follow-Up Studies
Graft Rejection
Humans
Infant
Kidney Diseases
Kidney Transplantation
Male
Postoperative Complications
Recurrence
Registries
| | Abstract | Of the 4,776 first grafts recorded in the pediatric European Dialysis and Transplant Association (EDTA) registry, 2,113 were reported to have failed and 5.6% of graft failures were related to a recurrence of primary renal disease. Nephrotic syndrome with focal and segmental glomerulosclerosis was the main renal disease prone to recur because recurrence represented 20% of the causes of graft failure in these patients; an even higher proportion was reported in a single-center experience in Europe. Other glomerulonephropathies, such as membranoproliferative glomerulonephritis and Berger's disease, were also reported to be the cause of graft failure by means of recurrence in a proportion similar to focal and segmental glomerulosclerosis. The usual recurrence of primary oxaluria was the cause of close to 50% of graft failure in this disease. Finally, hemolytic uremic syndrome recurred rarely with the graft in the EDTA registry, which is the opposite of what was reported in the United States. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 1498284 |
|
