| Title | [Angiosarcoma following breast-conserving therapy] | | Author(s) | Hogewind BF, Boutkan HB, de Jager-Nowak HK, Merkus JW | | Source | Ned Tijdschr Geneeskd 2004 May 15; 148(20):995-7. | | MeSH | Aged
Breast Neoplasms
Combined Modality Therapy
English Abstract
Fatal Outcome
Female
Hemangiosarcoma
Humans
Mastectomy, Segmental
Middle Aged
Neoplasm Recurrence, Local
Neoplasms, Radiation-Induced
Neoplasms, Second Primary
Postoperative Complications
Radiotherapy, Adjuvant
Reoperation
| | Abstract | Two women with breast cancer, 59 and 72 years of age, were treated by means of breast-conserving surgery and radiotherapy. At the age of 66 and 77, respectively, discolouration of the skin was seen in the treated breast. Punch biopsy did not show secondary malignancy. Diagnostic (deeper) excisional biopsy revealed angiosarcoma. Ablation of the breast was performed in both patients. The younger woman, however, had a recurrence four months later that was treated with wide local excision and omentum-plasty. The older woman died two years after the ablation as a result of haematogenous metastases. Knowledge of the symptoms and diagnostic pitfalls of radiotherapy-induced angiosarcoma after breast-conserving treatment is important in the follow-up of breast-cancer patients. Histological diagnosis of a biopsy taken at sufficient depth is indicated when a secondary angiosarcoma is suspected. | | Language | dut | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 15181725 |
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