Enantioselective total synthesis of valeriananoids A-C. Organic letters. [Org Lett] Journal article

[reaction: see text] The first enantioselective total synthesis of valeriananoids A-C (-)-1-3 is reported starting from the readily available monoterpene (R)-carvone, employing a tandem intermolecular Michael addition-intramolecular Michael addition-alkylation sequence and an electron-transfer-mediated 6-endo-trig cyclization as key steps.

Organic letters. [Org Lett]

Alkylation
Catalysis
Cyclization
Indicators and Reagents
Molecular Structure
Monoterpenes
Research Support, Non-U.S. Gov't
Sesquiterpenes
Stereoisomerism
Terpenes
Valerian