| Title | [Late hemorrhagic disease in newborn infants. Is the current preventive treatment with oral vitamin K adequate?] |
| Author(s) | Hansen KN, Tegllund L, Lange A, Ebbesen F |
| Institution | Børneafdelingen, Aalborg Sygehus. |
| Source | Ugeskr Laeger 1992 Apr 13; 154(16):1095-7. |
| MeSH | Administration, Oral
Cerebral Hemorrhage
English Abstract
Female
Hemorrhagic Disease of Newborn
Humans
Infant
Infant, Newborn
Umbilicus
Vitamin K
Vitamin K Deficiency
|
| Abstract | During recent years, we have observed two cases of haemorrhage due to vitamin K deficiency which developed late in the neonatal period. One patient was a female infant aged six weeks with severe intracranial bleeding and the other was a female infant aged three weeks with marked haemorrhage from the umbilicus. Both of these infants were entirely breast-fed and had received vitamin K (1 mg fytomenadion) orally at birth. Both infants had unrecognized alfa-1-antitrypsin deficiency with liver involvement. In other European countries, many cases of late haemorrhagic disease of the newborn due to vitamin K deficiency have been registered in infants who had received oral vitamin K prophylaxis. On the basis of these observations and investigations which suggest that oral vitamin K prophylaxis is not so effective as intramuscular administration, it is suggested that the present oral vitamin K prophylaxis should be altered. |
| Language | dan |
| Pub Type(s) | Case Reports
Journal Article
|
| PubMed ID | 1523716 |
