| Title | Ictal MEG in two children with partial seizures. | | Author(s) | Yoshinaga H, Ohtsuka Y, Watanabe Y, Inutsuka M, Kitamura Y, Kinugasa K, Oka E | | Institution | Department of Child Neurology, Okayama University Medical School, Shikatacho 2-5-1, Okayama 700-8558, Japan. magenta@md.okayama-u.ac.jp | | Source | Brain Dev 2004 Sep; 26(6):403-8. | | MeSH | Cerebral Cortex
Child
Child, Preschool
Electroencephalography
Epilepsies, Partial
Female
Humans
Laterality
Magnetic Resonance Imaging
Magnetoencephalography
Male
Nervous System Malformations
Occipital Lobe
Predictive Value of Tests
Reproducibility of Results
Temporal Lobe
Tomography, Emission-Computed, Single-Photon
| | Abstract | We report on the successful identification of epileptic foci in two children with partial epilepsy using ictal magnetoencephalography (MEG). Case 1 is a 12-year-old male suffering with simple partial seizures with leftwards nystagmus. Ictal SPECT revealed a hyperperfusion area in the right lateral occipital area, and MRI revealed cortical dysplasia in the same area. Interictal EEG dipoles were concentrated in the right mesial occipital lobe. Both interictal and ictal MEG dipoles were concentrated in the right mesial occipital lobe, which corresponded well with neuroimaging data and his clinical features. Case 2 is a 5-year-old female suffering with simple partial seizures with left-side facial twitching. Interictal EEG dipoles were located in her left motor area, the pre-sylvian fissure, close to the location of the interictal MEG-estimated dipoles. Ictal EEGs showed no remarkable changes associated with her clinical manifestations. However, ictal MEG showed high-voltage slow waves over her left hemisphere, and ictal MEG iso-contour maps revealed a clear dipolar pattern, which suggested that the MEG dipole was located in the area of the sylvian fissure. Ictal SPECT revealed hyperperfusion areas around the left sylvian fissure.
Conclusion: Ictal MEG is useful for determining the precise location of epileptic focus in patients with motionless seizures, including children. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 15275705 |
|
