| Title | [Vitamin B(12) deficiency anaemia in a 7.5 months old girl] | | Author(s) | Jarosz M, Irga N, Wierzba J | | Institution | Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, Debinki 7, 80-211 Gdańsk, Poland. m.jarosz@amg.gda.pl | | Source | Med Wieku Rozwoj 2004 Apr-Jun; 8(2 Pt 1):283-8. | | MeSH | Adult
Anemia, Pernicious
Breast Feeding
Diagnosis, Differential
Diet, Vegetarian
English Abstract
Female
Humans
Infant
Infant Nutrition
Infant Nutrition Disorders
Leukemia, Lymphocytic, Acute, L1
Pregnancy
Pregnancy Complications, Hematologic
Time Factors
Treatment Outcome
Vitamin B 12
Vitamin B 12 Deficiency
| | Abstract | Vitamin B(12) stores at birth are adequate for infants until the end of the first year of life even if it 's concentration in maternal breast milk is low. However, there are some situations in which infants have depleted vitamin B(12) stores and in addition have a low dietary intake of cobalamin. Vitamin B(12) depletion occurs in infants who are exclusively breastfed by mothers who have unrecognized pernicious anemia or are strict vegetarians for many years. In those infants symptoms of bone marrow disfunction and impaired development of the central nervous system appear already in the first months of life. Unrecognized cobalamin deficiency may lead to serious neurologic consequences, and even to the death of the child. The authors present a case of a 7.5 month old girl admitted to the Department of Paediatrics, Haematology, Oncology and Endocrinology. Gdańsk Medical University suspected of acute leukaemia. Based on a detailed diagnostic procedure a final diagnosis of vitamin B(12) deficiency anaemia was established. The child was exclusively breast-fed. Results of investigations into the reason for cobalamin deficiency in the patient s organism. Led to the diagnosis of pernicious anaemia in the mother. Such a suspicion had been made during pregnancy, but no continuation of investigations nor appropriate treatment were implemented. After treatment with vitamin B(12) supplements and modification of the diet the patient improved quickly and remarkably. A few months follow-up was enough to observe remarkable improvement of psychomotor development of this child. | | Language | pol | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 15738604 |
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