Unbound MEDLINE

Two-once-daily fixed-dose NRTI combinations for HIV. The Medical letter on drugs and therapeutics. [Med Lett Drugs Ther] Journal article

 
TitleTwo-once-daily fixed-dose NRTI combinations for HIV.
SourceMed Lett Drugs Ther 2005 Feb 28; 47(1203):19-20.
MeSHAnti-HIV Agents
Deoxycytidine
Dose-Response Relationship, Drug
Drug Combinations
Drug Hypersensitivity
HIV Infections
Humans
Lamivudine
Organophosphorus Compounds
AbstractAbacavir/lamivudine (Epzicom) and emtricitabine/tenofovir (Truvada), two new once-daily fixed-dose NRTI combinations, have been approved for use in antiretroviral regimens to treat HIV infection. Epzicom appears to be as effective as its components taken separately and, in one study, Truvada was at least as effective as zidovudine/lamivudine (Combivir). Use of once-daily fixed-dose combinations means less flexibility in dosing, and some patients with hepatic or renal impairment will not be able to take them.
Languageeng
Pub Type(s)Journal Article
PubMed ID15767973
  
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