| Title | Assignment of steatotic livers by the Mayo model for end-stage liver disease. | | Author(s) | Briceño J, Padillo J, Rufián S, Solórzano G, Pera C | | Institution | Unit of Liver Transplantation, Department of Surgery, Hospital Reina Sofía, Córdoba, Spain. javibriceno@hotmail.com | | Source | Transpl Int 2005 May; 18(5):577-83. | | MeSH | Adolescent
Adult
Aged
Donor Selection
Fatty Liver
Female
Graft Survival
Humans
Liver Failure
Liver Transplantation
Male
Middle Aged
Models, Biological
Prognosis
Spain
Survival Rate
Tissue Donors
Tissue and Organ Procurement
| | Abstract | Prognosis after liver transplantation depends on a combination of recipient and donor variables. The purpose of this study is to define an allocation system of steatotic donor livers relative to recipient model for end-stage liver disease (MELD) score. We reviewed 500 consecutive OLT, computing the MELD score for each recipient. Fatty infiltration in grafts was categorized in no steatosis, 10-30%, 30-60% and > or = 60% steatosis. MELD score did not affect preservation injury and graft dysfunction, which were increased with fat content. Recipient and graft survivals lowered when increasing MELD score. Outcome in low-risk recipients (MELD < or = 9) was not altered with steatosis, except those with > or = 60%. Survival functions in moderate-risk recipients (MELD 10-19) were moderately affected with 10-30% steatosis and severely with those with >30. Exactly 30-60% steatotic grafts work poorly in high-risk recipients (MELD > or = 20), and very poorly with > or = 60% steatosis. Prognosis of candidates is optimally influenced when divergence of recipient-donor risks is presented. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 15819807 |
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