| Title | Determination of diethanolamine in shampoo products containing fatty acid diethanolamides by liquid chromatography with a thermal energy analyzer. | | Author(s) | Chou HJ | | Institution | U.S. Food and Drug Administration, 5100 Paint Branch Pkwy, College Park, MD 20740, USA. hchou@cfsan.fda.gov | | Source | J AOAC Int 2005 Mar-Apr; 88(2):592-4. | | MeSH | Algorithms
Chemiluminescent Measurements
Chromatography, Liquid
Ethanolamines
Fatty Acids
Indicators and Reagents
Nitroso Compounds
Soaps
Spectrophotometry, Ultraviolet
| | Abstract | A liquid chromatography (LC) method using a thermal energy analyzer (TEA) is described for the determination of diethanolamine (DEA) in shampoo products containing fatty acid diethanolamides. DEA was converted to N-nitrosodiethanolamine (NDELA) by dissolving a portion of the product in 6M acetic acid and mixing with sodium nitrite for 1 h at room temperature. The reaction mixture was dried, dissolved in acetone, and analyzed for NDELA by LC-TEA. The recovery of DEA from 2 shampoo products at fortification levels of 25, 250, and 1000 ppm ranged from 70 to 105%. Twenty shampoo products were analyzed by this method, and 19 were found to contain DEA at levels ranging from 140 to 15 200 ppm. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 15859088 |
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