| Title | Topical metronidazole combination therapy in the clinical management of rosacea. | | Author(s) | Del Rosso JQ, Bikowski J | | Institution | Department of Dermatology, University of Nevada School of Medicine, Las Vegas, NV, USA. | | Source | J Drugs Dermatol 2005 Jul-Aug; 4(4):473-80. | | MeSH | Administration, Topical
Adult
Aged
Disease Management
Doxycycline
Drug Therapy, Combination
Female
Follow-Up Studies
Humans
Male
Metronidazole
Middle Aged
Rosacea
Sulfacetamide
| | Abstract | Metronidazole was the first topical agent approved by the U.S. Food and Drug Administration for the treatment of rosacea. Several controlled studies have confirmed the efficacy and safety of topical metronidazole 0.75% gel, lotion and cream and 1% cream for rosacea. At present, little data exists regarding the use of combination topical therapy in rosacea management, although anecdotal evidence and preliminary studies suggest at least some additive benefit when topical metronidazole is used in combination with sulfacetamide 10% /sulfur 5%. In this paper, the results of observational experience evaluating topical metronidazole 0.75% gel used in combination with other topical rosacea therapies and/or subantimicrobial dose doxycycline are reported. | | Language | eng | | Pub Type(s) | Journal Article
Review
| | PubMed ID | 16004021 |
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