Unbound MEDLINE

Antiphospholipid antibodies. Clinical advances in hematology & oncology : H&O [Clin Adv Hematol Oncol] Journal article

 
Triplett DA 
Antiphospholipid antibodies. [Journal Article]
Clin Adv Hematol Oncol 2003 Dec; 1(12):726-30.


Antiphospholipid antibodies (APAs) have been associated with thromboembolic events. Since they were fi rst described in 1906, APAs have been the subject of multidisciplinary studies seeking to link them to potential pathophysiologic mechanisms. This review summarizes the different types of APAs, antigenic targets, clinical complications associated with APAs, and APA syndrome. In addition, the currently available methods for laboratory identificiation of lupus anticoagulants are discussed, as is the laboratory diagnosis of anticardiolipin antibodies.



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