Budd-Chiari syndrome, systemic lupus erythematosus, and secondary antiphospholipid antibody syndrome in pregnancy. Obstetrics and gynecology. [Obstet Gynecol] Journal article

Title	Budd-Chiari syndrome, systemic lupus erythematosus, and secondary antiphospholipid antibody syndrome in pregnancy.
Author(s)	Joffe GM, Aisenbrey GA, Argubright KF
Institution	Perinatal Associates of New Mexico, Albuquerque, New Mexico 87106, USA. gioffe1@comcast.net
Source	Obstet Gynecol 2005 Nov; 106(5 Pt 2):1191-4.
MeSH	Adult Antibodies, Antiphospholipid Antiphospholipid Syndrome Cholecystectomy, Laparoscopic Combined Modality Therapy Enoxaparin Female Fibrinolytic Agents Hepatic Vein Thrombosis Humans Liver Liver Function Tests Lupus Erythematosus, Systemic Pregnancy Pregnancy Complications, Cardiovascular Pregnancy Outcome
Abstract	BACKGROUND: Hypercoaguable states such as the antiphospholipid antibody syndrome may be associated with thromboses in any vascular bed. CASE: This case report demonstrates clinical manifestations of Budd-Chiari syndrome during pregnancy, diagnostic dilemmas, and suggestions for prevention of serious thromboembolic complications. CONCLUSION: Patients with antiphospholipid antibody syndrome and previous thromboses in any vascular bed who are considering pregnancy should be considered candidates for full anticoagulation throughout the entirety of gestation and the puerperium. Anti-Xa levels may reflect inadequate dosing of low molecular weight heparin, particularly during the first trimester, and should be monitored frequently. In patients with suspected hepatic venous thrombosis, Doppler evaluation may be inadequate to establish the diagnosis.
Language	eng
Pub Type(s)	Case Reports Journal Article
PubMed ID	16260568

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