| Title | [Bronchiectasis worsening by p-ANCA (bactericidal/permeability-increasing protein) positive vasculitis. A case report and review of the literature] | | Author(s) | Benucci M, Nenci G, Taccetti G, Rosso A, Beltrame C, Cappelletti C, Manfredi M | | Institution | Sezione di Reumatologia, Dipartimento di Medicina Interna, Nuovo Ospedale San Giovanni di Dio di Firenze. maubenucci@tiscali.it | | Source | Ann Ital Med Int 2005 Oct-Dec; 20(4):258-61. | | Abstract | A 67-year-old woman was hospitalized with recurrent fever, arthralgia and erythema of the arms and legs. She had suffered from bronchiectasis for the previous 4 years, and Pseudomonas was persistently detected in her sputum. During the course of her illness, she developed distal sensitive and motor polyneuropathy. Serum test was positive for myeloperoxidase and bactericidal/permeability-increasing protein antineutrophil cytoplasmic antibodies. Nerve biopsy showed vasculitis infiltration of the vasa nervorum. She started immunoglobulin therapy, and after methylprednisolone and pulse cyclophosphamide therapy once monthly for 6 months she showed a good response and a reduction in symptoms. | | Language | ita | | Pub Type(s) | Journal Article
| | PubMed ID | 16610259 |
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