| Title | Antioxidant Properties of Methanolic Extracts from Leaves of Rhazya stricta. | | Author(s) | Iqbal S, Bhanger MI, Akhtar M, Anwar F, Ahmed KR, Anwer T | | Institution | Departments of Chemistry , University of Sargodha, Sargodha, Pakistan. | | Source | J Med Food 2006; 9(2):270-5. | | Abstract | Because of increased safety concerns about synthetic antioxidants, exploitation of cheaper and safer sources of antioxidants based on natural origin is the focus of research nowadays. Rhazya stricta is a medicinally important plant native to South Asia. Extraction of antioxidants was carried out in different solvent systems, i.e., water, 80% methanol, 70% ethanol, and diethyl ether. The methanolic extract exhibited the highest total phenolic content among the extracts; therefore for further studies the methanolic extract was employed. Antioxidant activity measurement in the linoleic acid system, metal chelating activity, reducing power, scavenging effect on 1,1-diphenyl-2-picrylhydrazyl free radical, and superoxide anion radical scavenging activity were taken as the parameters for assessment of antioxidant potential of methanolic extracts. Results were compared with alpha-tocopherol and the synthetic antioxidant butylated hydroxyanisole. The antioxidant potential of methanolic extracts of R. stricta leaves was comparable with previously exploited potent antioxidants and is strongly concentration dependent. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 16822215 |
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