| Title | Preoperative breast MRI for locoregional staging. | | Author(s) | Hollingsworth AB, Stough RG | | Institution | Mercy Women's Center, 4300 McAuley Blvd., Oklahoma City, OK 73120, USA. | | Source | J Okla State Med Assoc 2006 Oct; 99(10):505-15. | | Abstract | BACKGROUND: Magnetic resonance imaging of the breast is indicated in multiple settings, one of which is preoperative staging to establish tumor extent, multicentricity, and contralateral disease.
METHODOLOGY: Results of conventional imaging, breast MRI, and pathology were analyzed from 334 patients who underwent breast MRI subsequent to a biopsy that confirmed primary breast malignancy. The focus of this retrospective study was imaging-histologic correlation.
FINDINGS: Only 1.2% of patients with tumors mapped by MRI required re-operation after lumpectomy. Multicentricity was identified by MRI alone in 7.7% of patients, while 3.6% were found to have occult contralateral cancer. In 11 of the 12 patients with contralateral cancer, the lesion was invasive, with ductal histology in 9 of the 11. The sensitivity of mammography for detecting these contralateral cancers was only 22.2%.
CONCLUSION: Preoperative breast MRI is recommended for mapping tumor extent and to discover additional primary lesions in newly diagnosed breast cancer patients. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 17125104 |
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