| Title | Anthropometric Determinants of a Clustering of Lipid-Related Metabolic Risk Factors in Overweight and Non-Overweight Adolescents - Influence of Cardiorespiratory Fitness. The AVENA Study. | | Author(s) | Mesa JL, Ortega FB, Ruiz JR, Castillo MJ, Tresaco B, Carreño F, Moreno LA, Gutiérrez A, Bueno M | | Institution | Department of Medical Physiology, School of Medicine, University of Granada, Granada, Spain. | | Source | Ann Nutr Metab 2206 Dec 21; 50(6):519-527. | | Abstract | Background/Aims: To explore in adolescents the associations between simple anthropometric variables with a continuously distributed summary score for lipid-related metabolic risk in both overweight and non-overweight adolescents, and to test whether these associations are modified by the level of cardiorespiratory fitness. Methods: Cardiorespiratory fitness, BMI, skinfold thicknesses, body circumferences, and a continuously distributed clustering of lipid- related metabolic risk (calculated from LDL and HDL choles- terol, triglycerides, and glucose) were measured in 524 adolescents (265 males, 259 females, 15.3 +/- 1.4 years) from the cross-sectional multicentric AVENA study. Participants were classified as overweight (including obesity) or non-overweight. Results: Most anthropometric parameters were univariately related to the continuous lipid-related metabolic risk. However, after multicollinear analysis and generalized linear modelling, suprailiac skinfold thickness in males (p < 0.001, explained variance 12.2%) and waist-to-height ratio in females (p < 0.001, explained variance 10.0%) were the best determinants of the continuous metabolic risk score, after adjustment for age, sexual maturation, and economic status. These associations were slightly weakened in overweight males (p = 0.034) and females (p = 0.087), and did not interact with cardiorespiratory fitness. Conclusion: Our data emphasize the usefulness of suprailiac skinfold thickness in males and waist-to-height ratio in females as simple anthropometric measurements associated to an overall lipid-related metabolic risk, mainly in non-overweight adolescents and regardless their cardiorespiratory status. Copyright (c) 2006 S. Karger AG, Basel. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 17191028 |
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