| Title | [Cardiotoxic and neurotoxic effects after accidental intravascular bupivacaine administration : Therapy with lidocaine propofol and lipid emulsion.] | | Author(s) | Zimmer C, Piepenbrink K, Riest G, Peters J | | Institution | Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen, Hufelandstr. 55, 45122, Essen, Deutschland, christian.zimmer@uk-essen.de. | | Source | Anaesthesist 2007 Feb 3. | | Abstract | Accidental intravascular administration of bupivacaine can cause severe neurotoxic and cardiotoxic effects. We report a case of suspected bupivacaine intoxication due to intravascular injection via an epidural catheter and treatment with lidocain, propofol, and a 20% lipid emulsion resulting in fast resolution of cardiotoxic and neurotoxic effects. Possible mechanisms of action of the medications used are discussed. | | Language | GER | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 17277955 |
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