Cooper GM, Curry C, Barbano TE, Burrows AM, Vecchione LJ, Caccamese JF, Norbutt CS, Costello BJ, Losee JE, Moursi AM, Huard J, Mooney MP
Noggin Inhibits Postoperative Resynostosis in Craniosynostotic Rabbits. [JOURNAL ARTICLE]
J Bone Miner Res 2007 Apr 16.
Microabstract Inhibition of bone formation following surgery to correct craniosynostosis would alleviate the need for secondary surgeries and decrease morbidity and mortality. This study used a single dose of Noggin protein to prevent resynostosis and improve postoperative outcomes in a rabbit model of craniosynostosis.
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